Thio-aminopropyltriethoxysilane-modified porous glass-ceramics (TAMPG) were prepared through reuse of waste glass for efficient palladium (II) separation from wastewater. Novel TAMPG-1, TAMPG-2, TAMPG-3 were obtained by immobilizing organic ligands 2-thiophene formaldehyde, 2-mercaptobenzimidazoles and 2-mercaptobenzothiazole onto the surface of porous glass-ceramics made from waste glass. Optimal conditions for effective palladium (II) adsorption were investigated with respect to pH, temperature, initial concentration and contact time. Owing to cheap raw materials, good adsorption properties, great recycling potential, excellent selectivity and stability, an economically viable method was proposed for efficient palladium (II) separation from wastewater.